3115268-06-6
Chemical Structure
FKBP12 PROTAC FM4
- CAS No.: 3115268-06-6
- Formula:C73H89N7O17
- Molecular Weight:1336.52
InChIKey: VNHVSZVLLUUMCA-XHWPTSGRSA-N
SMILES: CC[C@@H](C1=CC(OC)=C(C(OC)=C1)OC)C(N2CCCC[C@H]2C(O[C@@H](C3=CC=CC(OCCNC(COCCOCCOCCOCCOCCNC(C4=CC=C(C=N4)C5=CC=C6N=CC(C(NC)=O)=C(C6=C5)NC7=CC=CC=C7)=O)=O)=C3)CCC8=CC(OC)=C(C=C8)OC)=O)=O
Biological Activity: FKBP12 PROTAC FM4 is a PROTAC degrader of FKBP12, with a DC50 value of 0.09-0.22 nM. FKBP12 PROTAC FM4 inhibits global protein synthesis, induces apoptosis, and selectively reduces the viability of cervical cancer cells expressing MTH1-E6 and FKBP12F36V-tagged SARS1. FKBP12 PROTAC FM4 is applicable to research related to HPV-positive cervical cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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FKBP12 PROTAC FM4 | 99.95% | FKBP12 PROTAC FM4 is a PROTAC degrader of FKBP12, with a DC50 value of 0.09-0.22 nM. FKBP12 PROTAC FM4 inhibits global protein synthesis, induces apoptosis, and selectively reduces the viability of cervical cancer cells expressing MTH1-E6 and FKBP12F36V-tagged SARS1. FKBP12 PROTAC FM4 is applicable to research related to HPV-positive cervical cancer. | ||||||||||||||||||||
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