3116767-83-7
3116767-83-7
Chemical Structure
TMLZ-G46
- CAS No.: 3116767-83-7
- Formula:C37H41N3O3
- Molecular Weight:575.74
InChIKey: PGUPWZSULUKZSH-UHFFFAOYSA-N
SMILES: O=C(/C(C#N)=C1C2=CC=CC=C2OC3=CC=CC=C3\1)NCCC4CCN(CC4)CC5=CC=C(C=C5)OCC6CCCCC6
Biological Activity: TMLZ-G46 is an orally active ZNF207 inhibitor with blood-brain barrier penetration ability, with a Kd value of 68 nM. TMLZ-G46 inhibits cancer cell proliferation, stemness, migration and invasion, induces G0/G1 cell cycle arrest and apoptosis, and suppresses colony formation. TMLZ-G46 can be used in glioma research[1].
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TMLZ-G46 | 98.45% | TMLZ-G46 is an orally active ZNF207 inhibitor with blood-brain barrier penetration ability, with a Kd value of 68 nM. TMLZ-G46 inhibits cancer cell proliferation, stemness, migration and invasion, induces G0/G1 cell cycle arrest and apoptosis, and suppresses colony formation. TMLZ-G46 can be used in glioma research. | ||||||||||||||||||||
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