3116771-70-8
3116771-70-8
Chemical Structure
PPARγ/δ modulator 2
- CAS No.: 3116771-70-8
- Formula:C17H17ClIN5O2Se
- Molecular Weight:564.67
InChIKey: KRUDFYPGGOUDIB-MBNYWOFBSA-N
SMILES: O[C@H](C[Se]1)[C@@H](O)[C@@H]1CN2C(N=C(Cl)N=C3NCC4=CC=CC(I)=C4)=C3N=C2
Biological Activity: PPARγ/δ modulator 2 (Compound 3h) is a PPARγ agonist and PPARδ antagonist. The Ki values for PPARγ and PPARδ are 2.8 μM and 43 nM, respectively. PPARγ/δ modulator 2 significantly enhances the production of Adiponectin and promotes adipogenic differentiation of human bone marrow mesenchymal stem cells (hBM-MSCs). PPARγ/δ modulator 2 can be used in the study of metabolic disorders associated with hypoadiponectinemia[1].
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PPARγ/δ modulator 2 | PPARγ/δ modulator 2 (Compound 3h) is a PPARγ agonist and PPARδ antagonist. The Ki values for PPARγ and PPARδ are 2.8 μM and 43 nM, respectively. PPARγ/δ modulator 2 significantly enhances the production of Adiponectin and promotes adipogenic differentiation of human bone marrow mesenchymal stem cells (hBM-MSCs). PPARγ/δ modulator 2 can be used in the study of metabolic disorders associated with hypoadiponectinemia. | |||||||||||||||||||||
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