3117797-30-2
3117797-30-2
Chemical Structure
XL-3156
- CAS No.: 3117797-30-2
- Formula:C28H23N9O2
- Molecular Weight:517.54
InChIKey: DJSJQMABIIXJLU-UHFFFAOYSA-N
SMILES: CC1=NN(C(O)=C1C(C2=C(N(N=C2C)C3=NC4=CC=CC=C4N3)O)C5=NC=CC=C5)C6=NC7=CC=CC=C7N6
Biological Activity: XL-3156 is a cGAS inhibitor. XL-3156 occupies both allosteric and orthosteric sites simultaneously, and inhibits the interaction and phase separation between cGAS and DNA by stabilizing the closed conformation of the activation loop. XL-3156 can be used in the research of diseases such as autoimmune diseases and inflammation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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XL-3156 | 99.91% | XL-3156 is a cGAS inhibitor. XL-3156 occupies both allosteric and orthosteric sites simultaneously, and inhibits the interaction and phase separation between cGAS and DNA by stabilizing the closed conformation of the activation loop. XL-3156 can be used in the research of diseases such as autoimmune diseases and inflammation. | ||||||||||||||||||||
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