3119282-44-6
3119282-44-6
Chemical Structure
(R,R)-MC-Val-Cit-PAB
- CAS No.: 3119282-44-6
- Formula:C28H40N6O7
- Molecular Weight:572.65
IUPAC Name: 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((R)-1-(((R)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)hexanamide
InChIKey: AMKBTTRWLGVRER-PXDATVDWSA-N
SMILES: CC([C@H](C(N[C@H](CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)NC(CCCCCN2C(C=CC2=O)=O)=O)C
Biological Activity: 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((R)-1-(((R)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)hexanamide is a biological molecule.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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(R,R)-MC-Val-Cit-PAB | 6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)-N-((R)-1-(((R)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)hexanamide is a biological molecule. | |||||||||||||||||||||
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Mc-Val-Cit-PAB-Cl | 95.0% | Mc-Val-Cit-PAB-Cl is a cleavable ADC linker. Mc-Val-Cit-PAB-Cl can be used to conjugate MMAE and antibody to form antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE with IC50s of 3.3 and 0.95 nM for BJAB and WSU cell lines in cytotoxicity assay). | ||||||||||||||||||||
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Mc-Val-Ala-PAB | 99.53% | Mc- Val- Ala- PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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Mal-PEG2-Val-Cit-PAB-OH | 99.49% | Mal-PEG2-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG2-Val-Cit-PAB-OH also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. | ||||||||||||||||||||
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Mal-PEG1-Val-Cit-PABC-OH | 95.12% | Mal-PEG1-Val-Cit-PABC-OH is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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MC-VC-PAB-NH2 | MC-VC-PAB-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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MC-VC-PAB-NH2 TFA | 99.89% | MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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Mal-amido-PEG2-Val-Cit-PAB-OH | Mal-amido-PEG2-Val-Cit-PAB-OH is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | |||||||||||||||||||||
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Mal-PEG2-Val-Cit-PABA | 98.91% | Mal-PEG2-Val-Cit-PABA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). | ||||||||||||||||||||
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6-Azidohexanoyl-Val-Cit-PAB-PNP | 6-Azidohexanoyl-Val-Cit-PAB-PNP is a click chemistry reagent that can be used to synthesis It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. | |||||||||||||||||||||
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MC-Val-Cit-PAB (GMP) | MC-Val-Cit-PAB GMP is a GMP grade MC-Val-Cit-PAB (HY-78738). MC-Val-Cit-PAB is an intermediate in the synthesis of VcMMAE (HY-15575), which is a Drug-Linker Conjugates for ADC. Monomethyl auristatin E can be used to inhibit Microtubule/Tubulin as ADC Cytotoxin. | |||||||||||||||||||||
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