3119457-09-6
3119457-09-6
Chemical Structure
VAV1 degrader-4
- CAS No.: 3119457-09-6
- Formula:C23H17ClF2N2O4
- Molecular Weight:458.84
InChIKey: BHICUONDPDTXMR-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)C2=CC=CC(C3=CC=C(N4C=CC=C(C4=O)OC(F)F)C=C3)=C2Cl)=O
Biological Activity: VAV1 degrader-4 is a VAV1 molecular glue degrader with a DC50 value of 3.93 nM for VAV1 in Jurkat cells. VAV1 degrader-4 can dose-dependently inhibit the production of IL-2. VAV1 degrader-4 can be used for research on autoimmune diseases[1].
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VAV1 degrader-4 | VAV1 degrader-4 is a VAV1 molecular glue degrader with a DC50 value of 3.93 nM for VAV1 in Jurkat cells. VAV1 degrader-4 can dose-dependently inhibit the production of IL-2. VAV1 degrader-4 can be used for research on autoimmune diseases. | |||||||||||||||||||||
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