3122394-70-8
3122394-70-8
Chemical Structure
PROTAC SARS-CoV-2 Mpro degrader-6
- CAS No.: 3122394-70-8
- Formula:C33H45N5O8
- Molecular Weight:639.74
InChIKey: JAGCBFFXWKAGSY-HMCKCBAOSA-N
SMILES: COC([C@@H](NC([C@@H](NC(CCCCCNC1=C2C(N(C3CCC(NC3=O)=O)C(C2=CC=C1)=O)=O)=O)C4CCCCC4)=O)C(C)C)=O
Biological Activity: PROTAC SARS-CoV-2 Mpro degrader-6 is a PROTACs degrader targeting the SARS-CoV-2 main protease (Mpro). PROTAC SARS-CoV-2 Mpro degrader-6 effectively induces the degradation of Mpro and increases K48-linked polyubiquitination of Mpro in HEK293 cells. PROTAC SARS-CoV-2 Mpro degrader-6 can be used in studies related to coronavirus disease 2019 (COVID-19)[1].
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PROTAC SARS-CoV-2 Mpro degrader-6 | PROTAC SARS-CoV-2 Mpro degrader-6 is a PROTACs degrader targeting the SARS-CoV-2 main protease (Mpro). PROTAC SARS-CoV-2 Mpro degrader-6 effectively induces the degradation of Mpro and increases K48-linked polyubiquitination of Mpro in HEK293 cells. PROTAC SARS-CoV-2 Mpro degrader-6 can be used in studies related to coronavirus disease 2019 (COVID-19). | |||||||||||||||||||||
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