3126213-85-9
3126213-85-9
Chemical Structure
UNC11676A
- CAS No.: 3126213-85-9
- Formula:C23H17F3N4O4S2
- Molecular Weight:534.53
InChIKey: GSCUHTUYLYQAPN-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(NC2=NC(C3=C(C)N=C(NC(C4=C(C(F)(F)F)C=CC=C4)=O)S3)=CS2)C=C1OC)O
Biological Activity: UNC11676A is an MDA5 ATPase inhibitor with IC50 values of 6 μM, 115 μM and 108 μM against MDA5, LGP2 and DDX1, respectively. MDA5, LGP2 and DDX1 are three human DExD/H-box RNA helicases. UNC11676A can be used in the research of Aicardi-Goutières syndrome, Singleton-Merten syndrome, systemic lupus erythematosus and Alzheimer's disease[1].
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UNC11676A | UNC11676A is an MDA5 ATPase inhibitor with IC50 values of 6 μM, 115 μM and 108 μM against MDA5, LGP2 and DDX1, respectively. MDA5, LGP2 and DDX1 are three human DExD/H-box RNA helicases. UNC11676A can be used in the research of Aicardi-Goutières syndrome, Singleton-Merten syndrome, systemic lupus erythematosus and Alzheimer's disease. | |||||||||||||||||||||
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