3126841-22-0
Chemical Structure
A3AR agonist 2
- CAS No.: 3126841-22-0
- Formula:C34H34N6O6
- Molecular Weight:622.67
InChIKey: GWPOXPCMLJYJKI-XSZVPTBZSA-N
SMILES: CNC([C@]12[C@@H](O)[C@@H](O)[C@H](N3C=NC4=C3N=C(C#CC5=CC=CC6=C5)N=C4NCCC7=CC(OC/C=C\CO6)=C(OC)C=C7)[C@H]1C2)=O
Biological Activity: A3AR agonist 2 (Compound 19) a selective A3AR agonist (Ki: 22.1 nM). A3AR agonist 2 stimulates β-arrestin2 recruitment, with EC50 value of 4.36 nM. A3AR agonist 2 can be used for research of inflammatory diseases, ischemia, cancer, neuropathic pain, liver diseases, and other chronic conditions[1]. A3AR agonist 2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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A3AR agonist 2 | A3AR agonist 2 (Compound 19) a selective A3AR agonist (Ki: 22.1 nM). A3AR agonist 2 stimulates β-arrestin2 recruitment, with EC50 value of 4.36 nM. A3AR agonist 2 can be used for research of inflammatory diseases, ischemia, cancer, neuropathic pain, liver diseases, and other chronic conditions. A3AR agonist 2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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