312722-60-4
Chemical Structure
NVP-SAA164
- CAS No.: 312722-60-4
- Formula:C36H45N5O5S
- Molecular Weight:659.84
IUPAC Name: (1-((4-((2,2-diphenylethyl)amino)-3-(morpholine-4-carbonyl)phenyl)sulfonyl)piperidin-4-yl)(4-methylpiperazin-1-yl)methanone
InChIKey: VODUCDWVPSEMSZ-UHFFFAOYSA-N
SMILES: O=C(N1CCOCC1)C2=CC(S(=O)(N3CCC(CC3)C(N4CCN(CC4)C)=O)=O)=CC=C2NCC(C5=CC=CC=C5)C6=CC=CC=C6
Biological Activity: NVP-SAA164 is an orally active nonpeptide kinin B1 receptor antagonist. NVP-SAA164 reverses CFA (Complete Freund's adjuvant) (HY-153808)-induced mechanical hyperalgesia and desArg10KD-induced hyperalgesia in hB1-KI mice, and is inactive in a model of inflammatory pain in wild-type mice[1].
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NVP-SAA164 | NVP-SAA164 is an orally active nonpeptide kinin B1 receptor antagonist. NVP-SAA164 reverses CFA (Complete Freund's adjuvant) (HY-153808)-induced mechanical hyperalgesia and desArg10KD-induced hyperalgesia in hB1-KI mice, and is inactive in a model of inflammatory pain in wild-type mice. | |||||||||||||||||||||
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