312773-04-9
312773-04-9
Chemical Structure
CKRPRAASFAE
- CAS No.: 312773-04-9
- Formula:C52H86N18O15S
- Molecular Weight:1235.42
InChIKey: HQYMMWAWZQUPHE-GXONDLQUSA-N
SMILES: O=C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CS)N
Biological Activity: CKRPRAASFAE is a glycogen synthase kinase 3-β-derived PKB/Akt peptide substrate that is used for in vitro kinase activity assays[1][2][3].
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CKRPRAASFAE | CKRPRAASFAE is a glycogen synthase kinase 3-β-derived PKB/Akt peptide substrate that is used for in vitro kinase activity assays. | |||||||||||||||||||||
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References
- [1]. Balasuriya N, et al. Genetic code expansion and live cell imaging reveal that Thr-308 phosphorylation is irreplaceable and sufficient for Akt1 activity. The Journal of biological chemistry. 2018 Jul 06;293(27):10744-10756.
- [2]. Wang Y, et al. Coordinated regulation of serum- and glucocorticoid-inducible kinase 3 by a C-terminal hydrophobic motif and Hsp90-Cdc37 chaperone complex. The Journal of biological chemistry. 2014 Feb 21;289(8):4815-26.
- [3]. Bai J, et al. Dual-readout fluorescent assay of protein kinase activity by use of TiO2-coated magnetic microspheres. Analytical chemistry. 2013 May 07;85(9):4813-21.
