3133114-23-2
Chemical Structure
URAT1-IN-18
- CAS No.: 3133114-23-2
- Formula:C14H7Cl2NO3S
- Molecular Weight:340.18
InChIKey: TXSHHFLRIPVPLY-UHFFFAOYSA-N
SMILES: O=C1SC2=CC=CC=C2N1C(C3=CC(Cl)=C(O)C(Cl)=C3)=O
Biological Activity: URAT1-IN-18 is an orally effective URAT1 inhibitor. URAT1-IN-18 inhibits URAT1-mediated urate transport and renal urate reabsorption. URAT1-IN-18 exhibits low cytotoxicity in vitro, with less apoptosis and loss of mitochondrial membrane potential. URAT1-IN-18 shows moderate metabolic stability in rat liver microsomes. URAT1-IN-18 reduces serum uric acid levels in a hyperuricemia mouse model, protects renal tubular structure, and has good biosafety. URAT1-IN-18 can be used for research related to hyperuricemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
URAT1-IN-18 | URAT1-IN-18 is an orally effective URAT1 inhibitor. URAT1-IN-18 inhibits URAT1-mediated urate transport and renal urate reabsorption. URAT1-IN-18 exhibits low cytotoxicity in vitro, with less apoptosis and loss of mitochondrial membrane potential. URAT1-IN-18 shows moderate metabolic stability in rat liver microsomes. URAT1-IN-18 reduces serum uric acid levels in a hyperuricemia mouse model, protects renal tubular structure, and has good biosafety. URAT1-IN-18 can be used for research related to hyperuricemia. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
