31528-46-8
Chemical Structure
6,7-Dehydro Norethindrone
Synonym(s): 6,7-Didehydronorethisterone
- CAS No.: 31528-46-8
- Formula:C20H24O2
- Molecular Weight:296.40
IUPAC Name: (8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: SWNFRSGMYREPFG-XGXHKTLJSA-N
SMILES: O[C@@]1(C#C)CC[C@@]2([H])[C@]3([H])C=CC4=CC(CC[C@]4([H])[C@@]3([H])CC[C@]12C)=O
Biological Activity: 6,7-Dehydro Norethindrone (6,7-Didehydronorethisterone) (Compound 26) is a Norethisterone (HY-B0554) metabolite. 6,7-Dehydro Norethindrone can be produced by the biotransformation of Norethisterone using Rhizopus microsporus PT2906. 6,7-Dehydro Norethindrone induces Apoptosis, binds to p53 and inhibits the degradation of p53. 6,7-Dehydro Norethindrone selectively exhibits antitumor activity against cervical cancer[1].
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6,7-Dehydro Norethindrone | 6,7-Dehydro Norethindrone (6,7-Didehydronorethisterone) (Compound 26) is a Norethisterone (HY-B0554) metabolite. 6,7-Dehydro Norethindrone can be produced by the biotransformation of Norethisterone using Rhizopus microsporus PT2906. 6,7-Dehydro Norethindrone induces Apoptosis, binds to p53 and inhibits the degradation of p53. 6,7-Dehydro Norethindrone selectively exhibits antitumor activity against cervical cancer. | |||||||||||||||||||||
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