31793-07-4
31793-07-4
Chemical Structure
Pirprofen
Synonym(s): SU 21524
- CAS No.: 31793-07-4
- Formula:C13H14ClNO2
- Molecular Weight:251.71
InChIKey: PIDSZXPFGCURGN-UHFFFAOYSA-N
SMILES: O=C(C(C)C1=CC=C(N2CC=CC2)C(Cl)=C1)O
Biological Activity: Pirprofen (SU 21524) is an orally active non-steroidal anti-inflammatory agent. pirprofen is a reversible prostaglandin synthetase inhibitor. Pirprofen inhibits leucocyte chemotaxis. Pirprofen shows anti-inflammatory, analgesic, antipyretic, ulcerogenic activities. Pirprofen inhibits the secondary phase of platelet aggregation induced by Collagen and Arachidonic acid (HY-109590). Pirprofen induces hepatitis[1][2].
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Pirprofen | Pirprofen (SU 21524) is an orally active non-steroidal anti-inflammatory agent. pirprofen is a reversible prostaglandin synthetase inhibitor. Pirprofen inhibits leucocyte chemotaxis. Pirprofen shows anti-inflammatory, analgesic, antipyretic, ulcerogenic activities. Pirprofen inhibits the secondary phase of platelet aggregation induced by Collagen and Arachidonic acid (HY-109590). Pirprofen induces hepatitis. | |||||||||||||||||||||
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References
- [1]. Todd PA, et al. Pirprofen. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy. Drugs. 1986 Dec;32(6):509-37. [Content Brief]
- [2]. Luders RC, et al. Disposition of pirprofen, a new anti-inflammatory drug. Clin Pharmacol Ther. 1977 Jun;21(6):721-30. [Content Brief]
