32381-28-5
Chemical Structure
Dimethyl diacetyl cystinate
Synonym(s): DACDM
- CAS No.: 32381-28-5
- Formula:C12H20N2O6S2
- Molecular Weight:352.43
IUPAC Name: dimethyl 3,3'-disulfanediyl(2R,2'R)-bis(2-acetamidopropanoate)
InChIKey: ZTTORBNKJFMGIM-UWVGGRQHSA-N
SMILES: CC(N[C@H](C(OC)=O)CSSC[C@H](NC(C)=O)C(OC)=O)=O
Biological Activity: Dimethyl diacetyl cystinate (DACDM) is a potent NF-κB inhibitor. Dimethyl diacetyl cystinate shifts the intracellular redox balance toward the oxidized state by increasing intracellular oxidized glutathione (GSSG) content, competitively blocking the binding of activated NF-κB to DNA, thereby inhibiting the production of inflammatory factors such as IL-1κ. Dimethyl diacetyl cystinate is promising for research of UVB-induced skin inflammation and related oxidative stress diseases[1].
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Dimethyl diacetyl cystinate | Dimethyl diacetyl cystinate (DACDM) is a potent NF-κB inhibitor. Dimethyl diacetyl cystinate shifts the intracellular redox balance toward the oxidized state by increasing intracellular oxidized glutathione (GSSG) content, competitively blocking the binding of activated NF-κB to DNA, thereby inhibiting the production of inflammatory factors such as IL-1κ. Dimethyl diacetyl cystinate is promising for research of UVB-induced skin inflammation and related oxidative stress diseases. | |||||||||||||||||||||
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