324022-01-7
324022-01-7
Chemical Structure
ERRγ inverse agonist 2
- CAS No.: 324022-01-7
- Formula:C27H21N5O2
- Molecular Weight:447.49
IUPAC Name: N-(3-amino-5-(pyridin-3-yloxy)phenyl)-1,3-diphenyl-1H-pyrazole-4-carboxamide
InChIKey: ODZPKVAISZKCGI-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C2=CC=CC=C2)N=C1C3=CC=CC=C3)NC4=CC(N)=CC(OC5=CC=CN=C5)=C4
Biological Activity: ERRγ inverse agonist 2 (compound 19) is a potent and selective ERRγ inverse agonist with a Kd value of 6.5 μM. ERRγ inverse agonist 2 inhibits the expression of hepcidin, fibrinogen and gluconeogenic genes. ERRγ inverse agonist 2 has antimicrobial, anti-coagulant and antidiabetic activities[1].
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ERRγ inverse agonist 2 | ERRγ inverse agonist 2 (compound 19) is a potent and selective ERRγ inverse agonist with a Kd value of 6.5 μM. ERRγ inverse agonist 2 inhibits the expression of hepcidin, fibrinogen and gluconeogenic genes. ERRγ inverse agonist 2 has antimicrobial, anti-coagulant and antidiabetic activities. | |||||||||||||||||||||
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