32571-49-6
32571-49-6
Chemical Structure
AQ-13
- CAS No.: 32571-49-6
- Formula:C16H22ClN3
- Molecular Weight:291.82
InChIKey: NCPLTAGJJVCHOW-UHFFFAOYSA-N
SMILES: ClC1=CC2=NC=CC(NCCCN(CC)CC)=C2C=C1
Biological Activity: AQ-13 (Compound 7) is a Chloroquine (HY-17589A) analogue with anti-breast cancer property. AQ-13 shows antiproliferative activities against MDA-MB231 and MCF7 with GI50 of 27.81 and 17.85 μM. AQ-13 shows low cytotoxicity against non-cancerous breast epithelial cells MCF10A (GI50 = 65.26 μM). AQ-13 can be used for the research of breast cancer[1].
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AQ-13 | AQ-13 (Compound 7) is a Chloroquine (HY-17589A) analogue with anti-breast cancer property. AQ-13 shows antiproliferative activities against MDA-MB231 and MCF7 with GI50 of 27.81 and 17.85 μM. AQ-13 shows low cytotoxicity against non-cancerous breast epithelial cells MCF10A (GI50 = 65.26 μM). AQ-13 can be used for the research of breast cancer. | |||||||||||||||||||||
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