327104-77-8
Chemical Structure
Sirtuin modulator 4
- CAS No.: 327104-77-8
- Formula:C18H10N2O2S
- Molecular Weight:318.35
IUPAC Name: 2-(benzo[d]thiazol-2-yl)-3-(benzofuran-2-yl)-3-oxopropanenitrile
InChIKey: QKHIBBWTWNUTNL-UHFFFAOYSA-N
SMILES: N#CC(C(C1=CC2=C(C=CC=C2)O1)=O)C3=NC4=C(S3)C=CC=C4
Biological Activity: Sirtuin modulator 4 (compound 12) is a sirtuin modulator. Sirtuin modulator 4 shows inhibitory effect to SIRT1 with an EC50 value of 51-100 μM. Sirtuin modulator 4 may be used for the research of increasing the lifespan of a cell, and preventing a wide variety of diseases and disorders including, for example, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, inflammation and cancer[1].
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Sirtuin modulator 4 | Sirtuin modulator 4 (compound 12) is a sirtuin modulator. Sirtuin modulator 4 shows inhibitory effect to SIRT1 with an EC50 value of 51-100 μM. Sirtuin modulator 4 may be used for the research of increasing the lifespan of a cell, and preventing a wide variety of diseases and disorders including, for example, diabetes, obesity, neurodegenerative diseases, cardiovascular diseases, inflammation and cancer. | |||||||||||||||||||||
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