329218-11-3
329218-11-3
Chemical Structure
Quetiapine sulfoxide dihydrochloride
Synonym(s): Quetiapine S-oxide dihydrochloride
- CAS No.: 329218-11-3
- Formula:C21H27Cl2N3O3S
- Molecular Weight:472.43
IUPAC Name: 11-(4-(2-(2-hydroxyethoxy)ethyl)piperazin-1-yl)dibenzo[b,f][1,4]thiazepine 5-oxide dihydrochloride
InChIKey: MPRQQJUQOLNAFP-UHFFFAOYSA-N
SMILES: OCCOCCN(CC1)CCN1C2=NC(C=CC=C3)=C3S(C4=C2C=CC=C4)=O.Cl[H].Cl[H]
Biological Activity: Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic[1]. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist[2].
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Quetiapine sulfoxide dihydrochloride | 98.63% | Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist. | ||||||||||||||||||||
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Quetiapine sulfoxide dihydrochloride (Standard) | ≥98% | Quetiapine sulfoxide (dihydrochloride) (Standard) is the analytical standard of Quetiapine sulfoxide (dihydrochloride). This product is intended for research and analytical applications. Quetiapine sulfoxide dihydrochloride (Quetiapine S-oxide dihydrochloride) is a main metabolite of Quetiapinem. Quetiapine is a second-generation antipsychotic. Quetiapine is a 5-HT receptors agonist and a dopamine receptor antagonist. | ||||||||||||||||||||
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References
- [1]. Remmerie B, et al. Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole. Clin Pharmacol Drug Dev. 2016 Nov;5(6):528-537. [Content Brief]
- [2]. Cross AJ, et al. Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models. Br J Pharmacol. 2016 Jan;173(1):155-66. [Content Brief]
