332858-46-5
332858-46-5
Chemical Structure
(+)-Cyclozonarone
- CAS No.: 332858-46-5
- Formula:C21H24O2
- Molecular Weight:308.41
InChIKey: BEQLAZCYIMTZCU-PZJWPPBQSA-N
SMILES: C[C@@]12C3=CC(C(C=CC4=O)=O)=C4C=C3CC[C@@]1([H])C(C)(CCC2)C
Biological Activity: (+)-Cyclozonarone is a benzoquinone derivative found in brown algae Dictyopteris undulata, with activity against T. cruzi epimastigotes, Tulahuen strains. (+)-Cyclozonarone inhibits growth of cancer and endothelial cells, and exhibits anti-leishmanial activity. (+)-Cyclozonarone can be used for the research of lung carcinoma, colon carcinoma, prostate carcinoma[1][2][3].
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(+)-Cyclozonarone | (+)-Cyclozonarone is a benzoquinone derivative found in brown algae Dictyopteris undulata, with activity against T. cruzi epimastigotes, Tulahuen strains. (+)-Cyclozonarone inhibits growth of cancer and endothelial cells, and exhibits anti-leishmanial activity. (+)-Cyclozonarone can be used for the research of lung carcinoma, colon carcinoma, prostate carcinoma. | |||||||||||||||||||||
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References
- [1]. Virginia Delgado, et al. Synthesis of racemic and chiral albicanol, albicanyl acetate and cyclozonarone: cytotoxic activity of ent-cyclozonarone. January 2008. Journal of the Brazilian Chemical Society. 19(7):1258-1263.
- [2]. Wijeratne EM, et al. Sesquiterpene quinones and related metabolites from Phyllosticta spinarum, a fungal strain endophytic in Platycladus orientalis of the Sonoran Desert. J Nat Prod. 2008 Feb;71(2):218-22. [Content Brief]
- [3]. Rosales Martínez A, et al. Cp2TiCl-catalyzed, concise synthetic approach to marine natural product (±)-cyclozonarone. Synthetic Communications, 49(19), 2554-2560.
