334829-66-2
334829-66-2
Chemical Structure
DL-Sulforaphane N-acetyl-L-cysteine
Synonym(s): SFN-NAC
- CAS No.: 334829-66-2
- Formula:C11H20N2O4S3
- Molecular Weight:340.48
IUPAC Name: N-acetyl-S-((4-(methylsulfinyl)butyl)carbamothioyl)-L-cysteine
InChIKey: IIHBKTCHILXGOT-KMYGYIBBSA-N
SMILES: CS(CCCCNC(SC[C@@H](C(O)=O)NC(C)=O)=S)=O
Biological Activity: DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is an orally active HDAC inhibitor and metabolite of sulforaphane (HY-13755) with longer half-life and better blood-brain barrier permeability. DL-Sulforaphane N-acetyl-L-cysteine activates autophagy-mediated downregulation of α-tubulin expression through the ERK pathway and can be used in cancer research[1][2].
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DL-Sulforaphane N-acetyl-L-cysteine | 99.0% | DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is an orally active HDAC inhibitor and metabolite of sulforaphane (HY-13755) with longer half-life and better blood-brain barrier permeability. DL-Sulforaphane N-acetyl-L-cysteine activates autophagy-mediated downregulation of α-tubulin expression through the ERK pathway and can be used in cancer research. | ||||||||||||||||||||
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DL-Sulforaphane N-acetyl-L-cysteine (Standard) | ≥98% | DL-Sulforaphane N-acetyl-L-cysteine (Standard) (SFN-NAC (Standard)) is the analytical standard of DL-Sulforaphane N-acetyl-L-cysteine (HY-132242). This product is intended for research and analytical applications. DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC) is an orally active HDAC inhibitor and metabolite of sulforaphane (HY-13755) with longer half-life and better blood-brain barrier permeability. DL-Sulforaphane N-acetyl-L-cysteine activates autophagy-mediated downregulation of α-tubulin expression through the ERK pathway and can be used in cancer research. | ||||||||||||||||||||
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References
- [1]. Liu HJ, et al. Sulforaphane-N-Acetyl-Cysteine Induces Autophagy Through Activation of ERK1/2 in U87MG and U373MG Cells. Cell Physiol Biochem. 2018;51(2):528-542. [Content Brief]
- [2]. Dashwood R H, et al. Dietary histone deacetylase inhibitors: from cells to mice to man[C]//Seminars in cancer biology. Academic Press, 2007, 17(5): 363-369.
