340306-87-8
340306-87-8
Chemical Structure
SIRT5 inhibitor 2
- CAS No.: 340306-87-8
- Formula:C18H12Cl2N2O3S
- Molecular Weight:407.27
IUPAC Name: (E)-1-allyl-5-((5-(2,3-dichlorophenyl)furan-2-yl)methylene)-2-thioxodihydropyrimidine-4,6(1H,5H)-dione
InChIKey: NASLGRREAVKNNT-FMIVXFBMSA-N
SMILES: C=CCN1C(/C(C(NC1=S)=O)=C/C2=CC=C(O2)C3=CC=CC(Cl)=C3Cl)=O
Biological Activity: SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with an IC50 value of 2.3 μM. SIRT5 inhibitor 2 has inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 can be used for researching cancer and neurodegenerative diseases[1].
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SIRT5 inhibitor 2 | SIRT5 inhibitor 2 (compound 49) is a potent SIRT5 inhibitor with an IC50 value of 2.3 μM. SIRT5 inhibitor 2 has inhibitory activity against the SIRT5-dependent desuccinylation. SIRT5 inhibitor 2 can be used for researching cancer and neurodegenerative diseases. | |||||||||||||||||||||
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