340997-02-6
Chemical Structure
2′′,3′′-Dihydroochnaflavone
- CAS No.: 340997-02-6
- Formula:C30H20O10
- Molecular Weight:540.47
IUPAC Name: (S)-2-(3-(4-(5,7-dihydroxy-4-oxochroman-2-yl)phenoxy)-4-hydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
InChIKey: VNCWZYPKAQUABQ-DEOSSOPVSA-N
SMILES: O=C1C2=C(O)C=C(O)C=C2OC(C3=CC(OC4=CC=C([C@H]5OC6=CC(O)=CC(O)=C6C(C5)=O)C=C4)=C(C=C3)O)=C1
Biological Activity: 2′′,3′′-Dihydroochnaflavone is a flavonoid/flavanone-type ether-linked biflavonoid anti-leukemic compound. 2′′,3′′-Dihydroochnaflavone exhibits significant cytotoxicity against P388 murine lymphocytic leukemia cells (IC50 = 3.1 μg/mL). It can be naturally extracted from the dried leaves of Quintinia acutifolia and has also been previously isolated and identified from Ochna interrima and Luxemburgia nobilis (both Ochnaceae plants). 2′′,3′′-Dihydroochnaflavone can be used in research related to anti-tumor (especially leukemia) applications[1].
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2′′,3′′-Dihydroochnaflavone | 2′′,3′′-Dihydroochnaflavone is a flavonoid/flavanone-type ether-linked biflavonoid anti-leukemic compound. 2′′,3′′-Dihydroochnaflavone exhibits significant cytotoxicity against P388 murine lymphocytic leukemia cells (IC50 = 3.1 μg/mL). It can be naturally extracted from the dried leaves of Quintinia acutifolia and has also been previously isolated and identified from Ochna interrima and Luxemburgia nobilis (both Ochnaceae plants). 2′′,3′′-Dihydroochnaflavone can be used in research related to anti-tumor (especially leukemia) applications. | |||||||||||||||||||||
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