342595-05-5
342595-05-5
Chemical Structure
TM5007
- CAS No.: 342595-05-5
- Formula:C24H20N2O6S4
- Molecular Weight:560.69
IUPAC Name: 5',5'''-(adipoylbis(azanediyl))bis(([2,3'-bithiophene]-4'-carboxylic acid))
InChIKey: USLUSWIVVBUXLU-UHFFFAOYSA-N
SMILES: O=C(NC1=C(C(O)=O)C(C2=CC=CS2)=CS1)CCCCC(NC3=C(C(O)=O)C(C4=CC=CS4)=CS3)=O
Biological Activity: TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung[1].
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TM5007 | TM5007 is a poent and orally active inhibitor of plasminogen activator inhibitor-1 (PAI-1) with an IC50 of 29 μM. TM5007 enhance fibrinolysis activity and inhibits coagulation. TM5007 also prevents the fibrotic process initiated by bleomycin in mouse lung. | |||||||||||||||||||||
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