34391-10-1
Chemical Structure
Milliamine A
- CAS No.: 34391-10-1
- Formula:C45H49N3O10
- Molecular Weight:791.88
IUPAC Name: 4-(acetoxymethyl)-5,5a-dihydroxy-1,1,7,9-tetramethyl-11-oxo-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulen-6-yl 2-(2-(2-(dimethylamino)benzamido)-3-hydroxybenzamido)benzoate
InChIKey: VTLYZTRDIRBJDH-BVRVJCKWSA-N
SMILES: O=C(O[C@H]1C(C)=C[C@]23[C@]1(O)[C@H](O)C(COC(C)=O)=C[C@@](C3=O)([H])[C@@]4([H])[C@@](C4(C)C)([H])C[C@H]2C)C5=CC=CC=C5NC(C6=CC=CC(O)=C6NC(C7=CC=CC=C7N(C)C)=O)=O
Biological Activity: Milliamine A is an alkaloid ingenol ester derivative and a toxic substance that can be isolated from the dried roots of Euphorbia millii Ch. des Moulins. Milliamine A induces respiratory arrest caused by circulatory system damage, ptosis, diarrhea, weakened respiration, decreased body temperature, tremors, dyspnea, clonic-tonic convulsions, hemorrhage, and congestion of the lungs and spleen in mice[1].
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Milliamine A | Milliamine A is an alkaloid ingenol ester derivative and a toxic substance that can be isolated from the dried roots of Euphorbia millii Ch. des Moulins. Milliamine A induces respiratory arrest caused by circulatory system damage, ptosis, diarrhea, weakened respiration, decreased body temperature, tremors, dyspnea, clonic-tonic convulsions, hemorrhage, and congestion of the lungs and spleen in mice. | |||||||||||||||||||||
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