34446-06-5
Chemical Structure
Matairesinol monoglucoside
- CAS No.: 34446-06-5
- Formula:C26H32O11
- Molecular Weight:520.53
IUPAC Name: (3R,4R)-3-(4-hydroxy-3-methoxybenzyl)-4-(3-methoxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)benzyl)dihydrofuran-2(3H)-one
InChIKey: FWRZDNFXFFWBGP-LHHMAMHXSA-N
SMILES: OC(C=C1)=C(OC)C=C1C[C@@H](C(OC2)=O)[C@H]2CC3=CC(OC)=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C=C3
Biological Activity: Matairesinol monoglucoside is a STING activator. Matairesinol monoglucoside modulates the STING-TBK1-IRF3 signaling axis, promotes STING transcriptional expression, increases TBK1 and IRF3 phosphorylation. Matairesinol monoglucoside induces IFN-α and IFN-β production, reduces HBV DNA, HBsAg, and HBeAg expression. Matairesinol monoglucoside can be used for the research of hepatitis b virus (hbv) infection[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Matairesinol monoglucoside | 99.42% | Matairesinol monoglucoside is a STING activator. Matairesinol monoglucoside modulates the STING-TBK1-IRF3 signaling axis, promotes STING transcriptional expression, increases TBK1 and IRF3 phosphorylation. Matairesinol monoglucoside induces IFN-α and IFN-β production, reduces HBV DNA, HBsAg, and HBeAg expression. Matairesinol monoglucoside can be used for the research of hepatitis b virus (hbv) infection. | ||||||||||||||||||||
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References
- [1]. Lin M, et al. The lignan compound matairesinol monoglucoside induces type I interferon production in HBV infection immunity by regulating STING signaling. RSC Med Chem. Published online October 3, 2025. [Content Brief]
- [2]. Koyama N, et al. Serotonin derivatives, major safflower (Carthamus tinctorius L.) seed antioxidants, inhibit low-density lipoprotein (LDL) oxidation and atherosclerosis in apolipoprotein E-deficient mice. J Agric Food Chem. 2006 Jul 12;54(14):4970-6. [Content Brief]
