345288-49-5
345288-49-5
Chemical Structure
endo CNTinh-03
- CAS No.: 345288-49-5
- Formula:C23H25NO5S
- Molecular Weight:427.51
InChIKey: MGMHBWAUAKEYAO-UHFFFAOYSA-N
SMILES: O=C(C1=C(NC(C2C(C3CCC2C3)C(O)=O)=O)SC(C)=C1C4=CC=C(C)C=C4)OC
Biological Activity: Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC50 is 4 μM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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endo CNTinh-03 | 99.96% | Endo CNTinh-03 is inhibitor for the elevation of cAMP and cGMP induced by agonist, such as G protein-coupled receptors, adenylate cyclase, and guanylate cyclase (IC50 is 4 μM). Endo CNTinh-03 inhibits cholera toxin- and Escherichia coli (STa) toxin- induced CFTR chloride current, ameliorates secretory diarrhea in mouse models, and prevents cyst growth in polycystic kidney disease model. | ||||||||||||||||||||
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