346689-77-8
346689-77-8
Chemical Structure
XR11576
Synonym(s): MLN576
- CAS No.: 346689-77-8
- Formula:C23H24N4O2
- Molecular Weight:388.46
IUPAC Name: (R)-N-(1-(dimethylamino)propan-2-yl)-4-methoxybenzo[a]phenazine-11-carboxamide
InChIKey: ACAXGYADTLFREX-CQSZACIVSA-N
SMILES: O=C(N[C@@H](CN(C)C)C)C1=C2C(N=C3C=CC4=C(C=CC=C4C3=N2)OC)=CC=C1
Biological Activity: XR11576 (MLN576) is an orally active inhibitor of topoisomerase I and II. XR11576 shows cytotoxicity against human and murine tumor cell lines (IC50: 6-47 nM)[1].
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XR11576 | XR11576 (MLN576) is an orally active inhibitor of topoisomerase I and II. XR11576 shows cytotoxicity against human and murine tumor cell lines (IC50: 6-47 nM). | |||||||||||||||||||||
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