34695-81-3
Chemical Structure
Sclerotioramine
- CAS No.: 34695-81-3
- Formula:C21H24ClNO4
- Molecular Weight:389.87
IUPAC Name: 5-chloro-3-((1E,3E)-3,5-dimethylhepta-1,3-dien-1-yl)-7-methyl-6,8-dioxo-2,6,7,8-tetrahydroisoquinolin-7-yl acetate
InChIKey: DOUKEKLEUAGITQ-NJHPPEEMSA-N
SMILES: O=C(C1(OC(C)=O)C)C(Cl)=C2C=C(/C=C/C(C)=C/C(C)CC)NC=C2C1=O
Biological Activity: Sclerotioramine (Compound 1), a red pigment, is an antioxidant compound. Sclerotioramine can be isolated from the endolichenic fungus Penicillium sp.-strain 1322P. Sclerotioramine has potent antibacterial activity with MICs of 3.125, 3.125 and 6.25 μg/mL for Bacillus subtilis, Bacillus megaterium and Shigella dysentery, respectively. Sclerotioramine also has significant antifungal activity against Pestalotiopsis theae, Cochliobolus miyabeanus and Exserohilum turcicum[1][2].
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Sclerotioramine | Sclerotioramine (Compound 1), a red pigment, is an antioxidant compound. Sclerotioramine can be isolated from the endolichenic fungus Penicillium sp.-strain 1322P. Sclerotioramine has potent antibacterial activity with MICs of 3.125, 3.125 and 6.25 μg/mL for Bacillus subtilis, Bacillus megaterium and Shigella dysentery, respectively. Sclerotioramine also has significant antifungal activity against Pestalotiopsis theae, Cochliobolus miyabeanus and Exserohilum turcicum. | |||||||||||||||||||||
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References
- [1]. Kawakami H, et al. Antioxidant compounds produced by endolichenic fungus Penicillium sp.-strain 1322P isolated from Pyxine subcinerea. Arch Microbiol. 2024 Mar 21;206(4):187. [Content Brief]
- [2]. Huang L, et al. Isolation and Characterization of Antimicrobial Metabolites from the Sophora tonkinensis-Associated Fungus Penicillium sp. GDGJ-N37. Molecules. 2024 Jan 10;29(2):348. [Content Brief]
