349561-46-2
349561-46-2
Chemical Structure
SCPI-3
- CAS No.: 349561-46-2
- Formula:C14H10BrN3O4
- Molecular Weight:364.15
InChIKey: SZMXFDAAPGEKDK-UHFFFAOYSA-N
SMILES: O=[N+]([O-])C1=CC2=C(C(OC)=C1)NC(C3=CC=C(Br)C=C3)=NO2
Biological Activity: SCPI-3 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.159 µM; AeSCP-x IC50 = 0.285 µM). SCPI-3 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 of 3.09 µM in Aag-2 cells). SCPI-3 shows insecticidal activity against Aedes aegypti with a LD50 of 12.3 µM[1].
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SCPI-3 | SCPI-3 is a potent and competitive mosquito sterol carrier protein-2 (SCP-2) inhibitor (AeSCP-2 IC50 = 0.159 µM; AeSCP-x IC50 = 0.285 µM). SCPI-3 exhibits physiological effects on cholesterol metabolism in cultured insect cells (IC50 of 3.09 µM in Aag-2 cells). SCPI-3 shows insecticidal activity against Aedes aegypti with a LD50 of 12.3 µM. | |||||||||||||||||||||
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