34994-11-1
34994-11-1
Chemical Structure
Hypusine
- CAS No.: 34994-11-1
- Formula:C10H23N3O3
- Molecular Weight:233.31
IUPAC Name: N6-((R)-4-amino-2-hydroxybutyl)-L-lysine
InChIKey: BZUIJMCJNWUGKQ-BDAKNGLRSA-N
SMILES: N[C@H](C(O)=O)CCCCNC[C@@H](CCN)O
Biological Activity: Hypusine is a natural amino acid. The post-translational synthesis of hypusine is mainly catalyzed by deoxyhypusine synthase (DHPS) and deoxyhypusine hydroxylase (DOHH)[1][2].
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Hypusine | Hypusine is a natural amino acid. The post-translational synthesis of hypusine is mainly catalyzed by deoxyhypusine synthase (DHPS) and deoxyhypusine hydroxylase (DOHH). | |||||||||||||||||||||
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References
- [1]. Shiba T,et al. Hypusine, a new amino acid occurring in bovine brain. Isolation and structural determination. Biochim Biophys Acta. 1971 Sep 21;244(3):523-31. [Content Brief]
- [2]. ark MH, et al. Hypusine, a polyamine-derived amino acid critical for eukaryotic translation. J Biol Chem. 2018 Nov 30;293(48):18710-18718. [Content Brief]
