359722-12-6
Chemical Structure
α1A Adrenoceptor antagonist-1
- CAS No.: 359722-12-6
- Formula:C34H34ClF3N4O4
- Molecular Weight:655.11
InChIKey: LVWZTQJDYGMOJW-UHFFFAOYSA-N
SMILES: O=C1OC2(CCN(CC2)CCCN3C(NC(C4=CC=C(C)C=C4)(C5=CC=C(C)C=C5)C3=O)=O)C6=CC(Cl)=CC=C6N1CC(F)(F)F
Biological Activity: α1A Adrenoceptor antagonist-1 is a selective α1A adrenoceptor antagonist with a human Ki <20 nM. α1A Adrenoceptor antagonist-1 exhibits activity against benign prostatic hyperplasia (BPH) to enable less hindered urine flow. α1A Adrenoceptor antagonist-1 relaxes α1a receptor-enriched urethral smooth muscle tissue without inducing hypotension. α1A Adrenoceptor antagonist-1 can be used for the research of benign prostatic hyperplasia (BPH)[1].
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α1A Adrenoceptor antagonist-1 | α1A Adrenoceptor antagonist-1 is a selective α1A adrenoceptor antagonist with a human Ki <20 nM. α1A Adrenoceptor antagonist-1 exhibits activity against benign prostatic hyperplasia (BPH) to enable less hindered urine flow. α1A Adrenoceptor antagonist-1 relaxes α1a receptor-enriched urethral smooth muscle tissue without inducing hypotension. α1A Adrenoceptor antagonist-1 can be used for the research of benign prostatic hyperplasia (BPH). | |||||||||||||||||||||
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