36284-95-4
Chemical Structure
N-Methyl-3-aminomethy-lindole
Synonym(s): MAMI
- CAS No.: 36284-95-4
- Formula:C10H12N2
- Molecular Weight:160.22
IUPAC Name: 1-(1H-indol-3-yl)-N-methylmethanamine
InChIKey: BIFJNBXQXNWYOL-UHFFFAOYSA-N
SMILES: C=1C=CC2=C(C1)NC=C2CNC
Biological Activity: N-Methyl-3-aminomethy-lindole (MAMI) is a substrate of barley N-methyltransferase and undergoes N-methylation catalyzed by NMT; N-Methyl-3-aminomethy-lindole is an intermediate in the biosynthesis of the indole alkaloid gramine from tryptophan via aminomethylindole and its N-methyl derivative. N-Methyl-3-aminomethy-lindole can be used in studies of indole alkaloid biosynthetic pathways[1][2].
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N-Methyl-3-aminomethy-lindole | N-Methyl-3-aminomethy-lindole (MAMI) is a substrate of barley N-methyltransferase and undergoes N-methylation catalyzed by NMT; N-Methyl-3-aminomethy-lindole is an intermediate in the biosynthesis of the indole alkaloid gramine from tryptophan via aminomethylindole and its N-methyl derivative. N-Methyl-3-aminomethy-lindole can be used in studies of indole alkaloid biosynthetic pathways. | |||||||||||||||||||||
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References
- [1]. Larsson KA, et al. N-Methyltransferase involved in gramine biosynthesis in barley: cloning and characterization. Phytochemistry. 2006 Sep;67(18):2002-8.
- [2]. Kokubo Y, et al. Distribution of the tryptophan pathway-derived defensive secondary metabolites gramine and benzoxazinones in Poaceae. Bioscience, biotechnology, and biochemistry. 2017 Mar;81(3):431-440.