36475-47-5
36475-47-5
Chemical Structure
3-Methylhistamine dihydrochloride
- CAS No.: 36475-47-5
- Formula:C6H13Cl2N3
- Molecular Weight:198.09
IUPAC Name: 2-(1-methyl-1H-imidazol-5-yl)ethan-1-amine dihydrochloride
InChIKey: KWEIZIDNCJBKIY-UHFFFAOYSA-N
SMILES: NCCC1=CN=CN1C.[H]Cl.[H]Cl
Biological Activity: 3-Methylhistamine dihydrochloride is a degradation product of histamine. 3-Methylhistamine dihydrochloride, a methylated product of histamine, is associated with immune response and shows upregulation in the vaccinated mice[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3-Methylhistamine dihydrochloride | 99.80% | 3-Methylhistamine dihydrochloride is a degradation product of histamine. 3-Methylhistamine dihydrochloride, a methylated product of histamine, is associated with immune response and shows upregulation in the vaccinated mice. | ||||||||||||||||||||
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3-Methylhistamine dihydrochloride (Standard) | ≥98% | 3-Methylhistamine (dihydrochloride) (Standard) is the analytical standard of 3-Methylhistamine (dihydrochloride). This product is intended for research and analytical applications. 3-Methylhistamine dihydrochloride is a degradation product of histamine. 3-Methylhistamine dihydrochloride, a methylated product of histamine, is associated with immune response and shows upregulation in the vaccinated mice. | ||||||||||||||||||||
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4-Methylhistamine dihydrochloride | 99.35% | 4-Methylhistamine hydrochloride is the dihydrochloride salt of 4-Methylhistamine (HY-W580721). 4-Methylhistamine hydrochloride is a potent and selective agonist of histamine 4 receptor (H4R) with a Ki of 50 nM. 4-Methylhistamine hydrochloride has a >100-fold selectivity for the hH4R over the other histamine receptor subtypes. 4-Methylhistamine hydrochloride can potently activate the hH4R (pEC50 = 7.4). 4-Methylhistamine hydrochloride can be used for the researches of cancer, inflammation and immunology, such as lung cancer and skin inflammation. | ||||||||||||||||||||
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Pi-Methylimidazoleacetic acid | Pi-Methylimidazoleacetic acid is a potential neurotoxin. | |||||||||||||||||||||
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Pi-Methylimidazoleacetic acid hydrochloride | 99.01% | Pi-Methylimidazoleacetic acid hydrochloride is a potential neurotoxin. | ||||||||||||||||||||
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5-Chloromethyl-1-propyl-1H-imidazole hydrochloride | 95.0% | 5-Chloromethyl-1-propyl-1H-imidazole hydrochloride is a drug intermediate for synthesis of various active compounds. | ||||||||||||||||||||
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Histamine dihydrochloride (Standard) | 99.96% | Histamine dihydrochloride (Standard) is the analytical standard of Histamine dihydrochloride (HY-B0722). This product is intended for research and analytical applications. Histamine dihydrochloride is the agonist for histamine receptor and a vasodilator. Histamine dihydrochloride is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine dihydrochloride affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine dihydrochloride can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma. | ||||||||||||||||||||
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Histamine | 99.99% | Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma. | ||||||||||||||||||||
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3-Methyl-L-histidine (Standard) | 99.99% | 3-Methyl-L-histidine is an endogenous amino acid that can be found in actin and myosin. | ||||||||||||||||||||
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1-Methylhistamine dihydrochloride | 99.89% | 1-Methylhistamine dihydrochloride is a histamine metabolite. | ||||||||||||||||||||
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1-Methylhistamine-d3 dihydrochloride | 99.91% | 1-Methylhistamine-d3 (dihydrochloride) is the deuterium labeled 1-Methylhistamine (dihydrochloride). 1-Methylhistamine dihydrochloride is a histamine metabolite. | ||||||||||||||||||||
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1-Methylhistamine | 1-Methylhistamine is a histamine (Him) metabolite. | |||||||||||||||||||||
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References
- [1]. Schayer RW, et al. Methyl derivatives of histamine; interaction with histamine metabolism. Agents Actions. 1975;5(3):231-235. [Content Brief]
- [2]. Gill EL, et al. Ultrahigh-Performance Liquid Chromatography-High-Resolution Mass Spectrometry Metabolomics and Lipidomics Study of Stool from Transgenic Parkinson's Disease Mice Following Immunotherapy. J Proteome Res. 2020;19(1):424-431. [Content Brief]
