36953-37-4
36953-37-4
Chemical Structure
4-Bromo-2-hydroxypyridine
Synonym(s): 4-Bromo-2-pyridone
- CAS No.: 36953-37-4
- Formula:C5H4BrNO
- Molecular Weight:174.00
IUPAC Name: 4-bromopyridin-2-ol
InChIKey: SSLMGOKTIUIZLY-UHFFFAOYSA-N
SMILES: OC1=NC=CC(Br)=C1
Biological Activity: 4-Bromo-2-hydroxypyridine (4-Bromo-2-pyridone) is a brominated pyridine/pyridone chemical building block. 4-Bromo-2-hydroxypyridine exists in tautomeric forms between 2-hydroxypyridine and pyridin-2 (1H)-one. 4-Bromo-2-hydroxypyridine is used for the synthesis of bromopyridone nucleoside analogs, phosphoramidite intermediates, and 4-phenylpyridin-2-one derivatives. 4-Bromo-2-hydroxypyridine is applied in studies on heterocyclic synthesis and oligonucleotide modification chemistry[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Bromo-2-hydroxypyridine | 99.04% | 4-Bromo-2-hydroxypyridine (4-Bromo-2-pyridone) is a brominated pyridine/pyridone chemical building block. 4-Bromo-2-hydroxypyridine exists in tautomeric forms between 2-hydroxypyridine and pyridin-2 (1H)-one. 4-Bromo-2-hydroxypyridine is used for the synthesis of bromopyridone nucleoside analogs, phosphoramidite intermediates, and 4-phenylpyridin-2-one derivatives. 4-Bromo-2-hydroxypyridine is applied in studies on heterocyclic synthesis and oligonucleotide modification chemistry. | ||||||||||||||||||||
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2-Bromo-3-pyridinol | 99.87% | 2-Bromo-3-pyridinol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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4-Bromo-2-fluoropyridine | 99.88% | 4-Bromo-2-fluoropyridine is a drug intermediate. | ||||||||||||||||||||
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4-Bromo-2-chloropyridine | 99.28% | 4-Bromo-2-chloropyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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2-Amino-4-bromopyridine | 99.98% | 2-Amino-4-bromopyridine (4-Bromopyridine-2-amine) is an important intermediate, which can be used for the synthesis of other active compounds. | ||||||||||||||||||||
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5-Bromo-3-pyridinol | 99.96% | 5-Bromo-3-pyridinol is a chemical and pharmaceutical intermediate that can be used in the research of biological activities. Chlorinated derivatives of 5-Bromo-3-pyridinol are potential fungicides. | ||||||||||||||||||||
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3-Bromopyridin-2-ol | 99.62% | 3-Bromopyridin-2-ol is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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2-Bromo-4-chloropyridine | 98.96% | 2-Bromo-4-chloropyridine is a halogenated pyridine derivative that serves as a synthetic intermediate. 2-Bromo-4-chloropyridine undergoes Suzuki-Miyaura coupling with 4-tert-butylphenylboronic acid (HY-W007389). 2-Bromo-4-chloropyridine facilitates the construction of compounds with broad-spectrum antibacterial activity. | ||||||||||||||||||||
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2-Bromo-4-fluoropyridine | 99.98% | 2-Bromo-4-fluoropyridine is a halogenated pyridine organic synthesis building block that can be used as an intermediate in organic synthesis-related research. | ||||||||||||||||||||
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4-Bromo-2-methylpyridine | 99.84% | 4-Bromo-2-methylpyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | ||||||||||||||||||||
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2-Bromo-4-iodopyridine | 2-Bromo-4-iodopyridine is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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References
- [1]. Rudra A, et al. Bromopyridone Nucleotide Analogues, Anoxic Selective Radiosensitizing Agents That Are Incorporated in DNA by Polymerases. The Journal of organic chemistry. 2015 Nov 06;80(21):10675-85.
- [2]. Mistry SN, et al. 4-Phenylpyridin-2-one Derivatives: A Novel Class of Positive Allosteric Modulator of the M1 Muscarinic Acetylcholine Receptor. Journal of medicinal chemistry. 2016 Jan 14;59(1):388-409. [Content Brief]
- [3]. Jörg M, et al. Development of Novel 4-Arylpyridin-2-one and 6-Arylpyrimidin-4-one Positive Allosteric Modulators of the M Muscarinic Acetylcholine Receptor. ChemMedChem. 2021 Jan 08;16(1):216-233. [Content Brief]
