37000-20-7
37000-20-7
Chemical Structure
Zinterol
Synonym(s): MJ 9184
- CAS No.: 37000-20-7
- Formula:C19H26N2O4S
- Molecular Weight:378.49
IUPAC Name: N-(2-hydroxy-5-(1-hydroxy-2-((2-methyl-1-phenylpropan-2-yl)amino)ethyl)phenyl)methanesulfonamide
InChIKey: XJBCFFLVLOPYBV-UHFFFAOYSA-N
SMILES: CS(=O)(NC1=CC(C(O)CNC(C)(C)CC2=CC=CC=C2)=CC=C1O)=O
Biological Activity: Zinterol (MJ 9184) is a potent and selective β2-adrenoceptor agonist[1]. Zinterol increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM[2].
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Zinterol | Zinterol (MJ 9184) is a potent and selective β2-adrenoceptor agonist. Zinterol increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM. | |||||||||||||||||||||
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References
- [1]. Gwee MC, et al. Pharmacological actions of a new -adrenoceptor agonist, MJ-9184-1, in anaesthetized cats. Br J Pharmacol. 1972 Nov;46(3):375-85. [Content Brief]
- [2]. Skeberdis VA, et al. Beta-2 adrenergic activation of L-type Ca2+ current in cardiac myocytes. J Pharmacol Exp Ther. 1997 Nov;283(2):452-61. [Content Brief]
