370572-36-4

MLS-0053105 Chemical Structure
370572-36-4

Chemical Structure

MLS-0053105

  • CAS No.: 370572-36-4
  • Formula:C15H14Cl3N3O2
  • Molecular Weight:374.65

InChIKey: ZGZGUAKCJRZXRV-UHFFFAOYSA-N

SMILES: O=C1C(Cl)=C(N2CCN(CC2)C)C(N1C3=CC=C(C(Cl)=C3)Cl)=O

Biological Activity: MLS-0053105, a chloromaleimide, is a selective BFL-1 inhibitor with an IC50 of 0.4 µM for Bfl-1/F-Bid. MLS-0053105 shows over 10 times less potent inhibition of Bcl-W, Bcl-2, and Bcl-XL and no activity against Bcl-B and Mcl-1[1].

Cat. No. Product Name Purity Description Pricing
HY-167881
MLS-0053105 98.89% MLS-0053105, a chloromaleimide, is a selective BFL-1 inhibitor with an IC50 of 0.4 µM for Bfl-1/F-Bid. MLS-0053105 shows over 10 times less potent inhibition of Bcl-W, Bcl-2, and Bcl-XL and no activity against Bcl-B and Mcl-1.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References