37280-35-6
Chemical Structure
Capreomycin IA
- CAS No.: 37280-35-6
- Formula:C25H44N14O8
- Molecular Weight:668.72
IUPAC Name: (S)-3,6-diamino-N-(((2S,5S,11S,15S,Z)-15-amino-11-((R)-2-amino-3,4,5,6-tetrahydropyrimidin-4-yl)-2-(hydroxymethyl)-3,6,9,12,16-pentaoxo-8-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-5-yl)methyl)hexanamide
InChIKey: JNIIDKODPGHQSS-MPSMQSNBSA-N
SMILES: O=C1[C@]([C@@]2(NC(N)=NCC2)[H])(NC(=O)\C(=C\NC(N)=O)\NC(=O)[C@H](CNC(C[C@H](CCCN)N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CN1)[H]
Biological Activity: Capreomycin IA is a bactericidal agent targeting bacterial ribosomes, with activity limited primarily to mycobacteria. Capreomycin IA blocks translocation of peptidyl-transfer RNA from the A to the P site to inhibit protein synthesis. Capreomycin IA exerts activity against Mycobacterium tuberculosis. Capreomycin IA can be used for the research of tuberculosis[1].
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Capreomycin IA | Capreomycin IA is a bactericidal agent targeting bacterial ribosomes, with activity limited primarily to mycobacteria. Capreomycin IA blocks translocation of peptidyl-transfer RNA from the A to the P site to inhibit protein synthesis. Capreomycin IA exerts activity against Mycobacterium tuberculosis. Capreomycin IA can be used for the research of tuberculosis. | |||||||||||||||||||||
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