372965-00-9
372965-00-9
Chemical Structure
Diethylamine NONOate diethylammonium salt
Synonym(s): DEA NONOate diethylamine
- CAS No.: 372965-00-9
- Formula:C8H22N4O2
- Molecular Weight:206.29
IUPAC Name: N',N'-diethyl-N-hydroxynitrous hydrazide compound with diethylamine (1:1)
InChIKey: LBJLVZKEUWCGIA-UHFFFAOYSA-N
SMILES: CCNCC.O=NN(O)N(CC)CC
Biological Activity: Diethylamine NONOate (DEA NONOate, diethylammonium salt) is a nitric oxide donor. Diethylamine NONOate is a potent antimicrobial agent, which can inhibit Escherichia coli growth. Diethylamine NONOate also can enhance preservation of the donor rat heart[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Diethylamine NONOate diethylammonium salt | 98.0% | Diethylamine NONOate (DEA NONOate, diethylammonium salt) is a nitric oxide donor. Diethylamine NONOate is a potent antimicrobial agent, which can inhibit Escherichia coli growth. Diethylamine NONOate also can enhance preservation of the donor rat heart. | ||||||||||||||||||||
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NOC-5 | 98.50% | NOC-5 is a diazeniumdiolate compound that belongs to the same family of NO donors. NOC-5 is able to increase intracellular XIAP and Aven levels, potentially leading to the inhibition of caspase-9 activity following increased mitochondrial permeability. | ||||||||||||||||||||
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N-Nitrosodibutylamine (Standard) | ≥98% | N-Nitrosodibutylamine (Standard) is the analytical standard of N-Nitrosodibutylamine. This product is intended for research and analytical applications. N-Nitrosodibutylamine (N-Nitroso-di-n-butylamine) is a nitrosamine enriched in the drinking water. | ||||||||||||||||||||
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MAHMA NONOate | MAHMA NONOate is a NO donor. MAHMA NONOate effectively inhibits platelet aggregation induced by either collagen or ADP. | |||||||||||||||||||||
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PAPA NONOate | 98.0% | PAPA NONOate is a NO donor with a NO release half-life of 77 min (22-25°C). PAPA NONOate may represent a potential research for impaired wound healing in diabetes by increasing the rate of collagen synthesis at the wound site. | ||||||||||||||||||||
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DETA NONOate | 98.10% | DETA NONOate (NOC 18) is an exogenous nitric oxide (NO) donor. DETA NONOate shows a slow release normal amounts of NO and long-acting. | ||||||||||||||||||||
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3-(2-Hydroxy-1-methyl-2-nitrosohydrazinyl)-N-methyl-1-propanamine | 3-(2-Hydroxy-1-methyl-2-nitrosohydrazinyl)-N-methyl-1-propanamine is an endogenous metabolite. 3-(2-Hydroxy-1-methyl-2-nitrosohydrazinyl)-N-methyl-1-propanamine is significantly affected by low-dose citrus pectin. | |||||||||||||||||||||
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N-Nitrosodiethylamine (Standard) | 99.98% | N-Nitrosodiethylamine (Standard) is the analytical standard of N-Nitrosodiethylamine. This product is intended for research and analytical applications. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver. | ||||||||||||||||||||
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Tetraethylammonium fluoride tetrahydrofluoride | Tetraethylammonium Fluoride Tetrahydrofluoride is a biochemical reagent that can be used as a biological material or organic compound for life science related research. | |||||||||||||||||||||
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N-Nitrosodipropylamine (Standard) | ≥98% | N-Nitrosodipropylamine (Standard) is the analytical standard of N-Nitrosodipropylamine. This product is intended for research and analytical applications. | ||||||||||||||||||||
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Triethylammonium bicarbonate buffer (1.0M pH 8.5) | 98.0% | Triethylammonium bicarbonate is a biochemical reagent that can be used to prepare buffer solutions that maintains the stable pH environment required for processes such as enzyme-catalyzed reactions . | ||||||||||||||||||||
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References
- [1]. Sysel AM, et al. Antimicrobial properties of diethylamine NONOate, a nitric oxide donor, against Escherichia coli: a pilot study. J Antibiot (Tokyo). 2021 Apr;74(4):260-265. [Content Brief]
- [2]. Du ZY, et al. The nitric oxide donor, diethylamine NONOate, enhances preservation of the donor rat heart. J Heart Lung Transplant. 1998 Nov;17(11):1113-20. [Content Brief]
