38455-99-1
38455-99-1
Chemical Structure
BuChE-IN-14
- CAS No.: 38455-99-1
- Formula:C31H36ClN3O5S
- Molecular Weight:598.15
InChIKey: KZAJTVRKNKAXAG-UHFFFAOYSA-N
SMILES: O=C(C1=CC(OC)=C(C(OC)=C1)OC)OCCN2CCN(CCCN3C4=C(SC5=CC(Cl)=CC=C53)C=CC=C4)CC2
Biological Activity: BuChE-IN-14 is a novel compound that selectively inhibits acetylcholinesterase (AChE) activity. BuChE-IN-14 showed a concentration-dependent inhibitory effect on AChE in rat brain in vitro experiments. BuChE-IN-14 can increase the extracellular acetylcholine (ACh) concentration in the rat hippocampus and striatum at a certain dose. BuChE-IN-14 may help improve memory impairment caused by cholinergic dysfunction[1].
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BuChE-IN-14 | BuChE-IN-14 is a novel compound that selectively inhibits acetylcholinesterase (AChE) activity. BuChE-IN-14 showed a concentration-dependent inhibitory effect on AChE in rat brain in vitro experiments. BuChE-IN-14 can increase the extracellular acetylcholine (ACh) concentration in the rat hippocampus and striatum at a certain dose. BuChE-IN-14 may help improve memory impairment caused by cholinergic dysfunction. | |||||||||||||||||||||
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