384829-65-6
384829-65-6
Chemical Structure
BMS-363131
- CAS No.: 384829-65-6
- Formula:C28H40N6O5
- Molecular Weight:540.65
IUPAC Name: (2S,3R)-3-(((R)-1-carbamimidoylpiperidin-3-yl)methyl)-4-oxo-1-(4-(6-phenylhexanoyl)piperazine-1-carbonyl)azetidine-2-carboxylic acid
InChIKey: FHCQLMSOTXBNCN-AKFKNWHVSA-N
SMILES: O=C(N1CCN(CC1)C(CCCCCC2=CC=CC=C2)=O)N3[C@@H]([C@H](C3=O)C[C@@H]4CN(CCC4)C(N)=N)C(O)=O
Biological Activity: BMS-363131 is a selective inhibitor for tryptase, with an IC50 <1.7 nM. BMS-363131 is hydrolytic stable at pH=7 and pH=9. BMS-363131 attenuates the astham in a guinea pig model[1].
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BMS-363131 | BMS-363131 is a selective inhibitor for tryptase, with an IC50 <1.7 nM. BMS-363131 is hydrolytic stable at pH=7 and pH=9. BMS-363131 attenuates the astham in a guinea pig model. | |||||||||||||||||||||
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