384835-48-7
Chemical Structure
C18 Ceramide-1-phosphate (d18:1/18:0) ammonium salt
- CAS No.: 384835-48-7
- Formula:C36H75N2O6P
- Molecular Weight:662.96
InChIKey: HPIRYNODPHIXSE-KPLZBHHASA-N
SMILES: CCCCCCCCCCCCCCCCCC(N[C@@H](COP(O)(O)=O)[C@H](O)/C=C/CCCCCCCCCCCCC)=O.N
Biological Activity: C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt) is a specific type of long-chain molecule found in murine skin[1]. C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt) promotes migration of both mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells at concentrations between 0.5-5 µM. C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt)’s levels are higher in CFPAC-1 pancreatic ductal adenocarcinoma cells than in pancreatic cancer stem cells[2].
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C18 Ceramide-1-phosphate (d18:1/18:0) ammonium salt | C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt) is a specific type of long-chain molecule found in murine skin. C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt) promotes migration of both mouse bone marrow-derived multipotent stromal cells and human umbilical vein endothelial cells at concentrations between 0.5-5 µM. C18 Ceramide-1-phosphate (d18:1/18:0) (ammonium salt)’s levels are higher in CFPAC-1 pancreatic ductal adenocarcinoma cells than in pancreatic cancer stem cells. | |||||||||||||||||||||
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References
- [1]. Yamashita, R., et al. Analysis of molecular species profiles of ceramide-1-phosphate and sphingomyelin using MALDI-TOF mass spectrometry Lipids 51(2),263-270 (2016). [Content Brief]
- [2]. Kuc, N., et al. Pancreatic ductal adenocarcinoma cell secreted extracellular vesicles containing ceramide-1-phosphate promote pancreatic cancer stem cell motility Biochem. Pharmacol. 156,458-466 (2018). [Content Brief]
