389614-94-2
389614-94-2
Chemical Structure
EA4
- CAS No.: 389614-94-2
- Formula:C19H17ClN2O2
- Molecular Weight:340.80
IUPAC Name: 7-chloro-6-(4-(diethylamino)phenyl)quinoline-5,8-dione
InChIKey: XAZVKSMDPVMMPP-UHFFFAOYSA-N
SMILES: O=C(C(C1=CC=C(N(CC)CC)C=C1)=C2Cl)C3=C(N=CC=C3)C2=O
Biological Activity: EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA. EA4 can inhibit rPLA2 with a Ki value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis[1].
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EA4 | EA4, a derivative of quinone, is an inhibitor for both rPLA and cPLA. EA4 can inhibit rPLA2 with a Ki value of 130 μM. EA4 can be used for the research of hemostasis, thrombosis, and erythropoiesis. | |||||||||||||||||||||
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References
- [1]. Shin, Hae Sook et al. Purification and characterization of a cytosolic, 42-kDa and Ca2+-dependent phospholipase A2 from bovine red blood cells: its involvement in Ca2+-dependent release of arachidonic acid from mammalian red blood cells. The Journal of biological chemistry vol. 277,23 (2002): 21086-94. [Content Brief]
