393781-65-2
Chemical Structure
cRGDfK-thioacetyl ester
- CAS No.: 393781-65-2
- Formula:C31H45N9O9S
- Molecular Weight:719.81
InChIKey: FXPPTLMPDATYHN-GPJHCHHRSA-N
SMILES: O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCNC(CSC(C)=O)=O)[C@H]1CC2=CC=CC=C2
Biological Activity: cRGDfK-thioacetyl ester is a selective αvβ3 integrin-binding peptide that mediates cellular uptake through integrins overexpressed on tumor cells. cRGDfK-thioacetyl ester is conjugated to maleimide-functionalized PLGA nanoparticles, which enhances nanoparticle uptake and improves accumulation and retention. cRGDfK-thioacetyl ester can be used in research related to tumor-targeted nanodelivery and cancer-targeted imaging[1].
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cRGDfK-thioacetyl ester | 98.20% | cRGDfK-thioacetyl ester is a selective αvβ3 integrin-binding peptide that mediates cellular uptake through integrins overexpressed on tumor cells. cRGDfK-thioacetyl ester is conjugated to maleimide-functionalized PLGA nanoparticles, which enhances nanoparticle uptake and improves accumulation and retention. cRGDfK-thioacetyl ester can be used in research related to tumor-targeted nanodelivery and cancer-targeted imaging. | ||||||||||||||||||||
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