400078-78-6
400078-78-6
Chemical Structure
HDAC6-IN-75
- CAS No.: 400078-78-6
- Formula:C13H12N2O4S
- Molecular Weight:292.31
InChIKey: ZSIKBIFOAPITGF-UHFFFAOYSA-N
SMILES: O=C(NO)C1=CC=C(NS(=O)(C2=CC=CC=C2)=O)C=C1
Biological Activity: HDAC6-IN-75 is a selective HDAC6 inhibitor with an IC50 of 0.17 nM against HDAC6. HDAC6-IN-75 induces the accumulation of acetylated α-tubulin in glioma cells. HDAC6-IN-75 triggers cell cycle changes, increases the SubG1 cell population, and promotes apoptosis in glioma cells and glioblastoma stem cells. HDAC6-IN-75 is applicable for glioma-related research[1].
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HDAC6-IN-75 | 99.86% | HDAC6-IN-75 is a selective HDAC6 inhibitor with an IC50 of 0.17 nM against HDAC6. HDAC6-IN-75 induces the accumulation of acetylated α-tubulin in glioma cells. HDAC6-IN-75 triggers cell cycle changes, increases the SubG1 cell population, and promotes apoptosis in glioma cells and glioblastoma stem cells. HDAC6-IN-75 is applicable for glioma-related research. | ||||||||||||||||||||
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