407627-60-5
Chemical Structure
AF647-NHS ester
- CAS No.: 407627-60-5
- Formula:C40H49N3O16S4
- Molecular Weight:956.09
IUPAC Name: 3-(2-((1E,3E)-5-((Z)-3,3-dimethyl-5-sulfo-1-(3-sulfopropyl)indolin-2-ylidene)penta-1,3-dien-1-yl)-3-(6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)-3-methyl-5-sulfo-3H-indol-1-ium-1-yl)propane-1-sulfonate
InChIKey: PIQXJQCAOCUQOD-UHFFFAOYSA-N
SMILES: O=C(ON(C1=O)C(CC1)=O)CCCCCC2(C3=CC([S](=O)(O)=O)=CC=C3[N+](CCC[S](=O)([O-])=O)=C2/C=C/C=C/C=C(C(C)(C4=C5)C)\N(C4=CC=C5[S](=O)(O)=O)CCC[S](=O)(O)=O)C
Biological Activity: AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AF647-NHS ester | 96.0% | AF647-NHS ester is an analog of Alexa Fluor 647 (AF647). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: Protect from light. | ||||||||||||||||||||
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References
- [1]. Fernandez A, et al. In vivo characterization of the biodistribution profile of amphipol A8-35. J Membr Biol. 2014;247(9-10):1043-1051. [Content Brief]
- [2]. Mukundan H, et al. Optimizing a waveguide-based sandwich immunoassay for tumor biomarkers: evaluating fluorescent labels and functional surfaces. Bioconjug Chem. 2009 Feb;20(2):222-30. [Content Brief]
