4088-22-6
Chemical Structure
N-Methyldioctadecylamine
Synonym(s): Dioctadecylmethylamine; MDOA
- CAS No.: 4088-22-6
- Formula:C37H77N
- Molecular Weight:536.01
IUPAC Name: N-methyl-N-octadecyloctadecan-1-amine
InChIKey: VFLWKHBYVIUAMP-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCCCCCCCCN(C)CCCCCCCCCCCCCCCCCC
Biological Activity: N-Methyldioctadecylamine (Dioctadecylmethylamine; MDOA) is a surfactant and an ionizable cationic helper lipid that can be used for the preparation of lipid nanoparticles. When used in combination with iPhos 9A1P9 (HY-W590683) in ionizable lipid nanoparticles (iPLNPs), N-Methyldioctadecylamine enables liver-selective mRNA expression. N-Methyldioctadecylamine supports initial in vitro and in vivo mRNA delivery screening for iPhos lipids[1].
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N-Methyldioctadecylamine | N-Methyldioctadecylamine (Dioctadecylmethylamine; MDOA) is a surfactant and an ionizable cationic helper lipid that can be used for the preparation of lipid nanoparticles. When used in combination with iPhos 9A1P9 (HY-W590683) in ionizable lipid nanoparticles (iPLNPs), N-Methyldioctadecylamine enables liver-selective mRNA expression. N-Methyldioctadecylamine supports initial in vitro and in vivo mRNA delivery screening for iPhos lipids. | |||||||||||||||||||||
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