409369-54-6
409369-54-6
Chemical Structure
(2R,3S)-Emricasan
Synonym(s): (2R,3S)-PF 03491390; (2R,3S)-IDN-6556
- CAS No.: 409369-54-6
- Formula:C26H27F4N3O7
- Molecular Weight:569.50
InChIKey: SCVHJVCATBPIHN-PXAZEXFGSA-N
SMILES: FC1=C(C(F)=C(C=C1F)F)OCC([C@@H](NC([C@H](NC(C(NC2=C(C=CC=C2)C(C)(C)C)=O)=O)C)=O)CC(O)=O)=O
Biological Activity: (2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan (HY-10396). Emricasan is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV)-induced increases in caspase-3 activity and protected human cortical neural progenitors[1].
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(2R,3S)-Emricasan | (2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan (HY-10396). Emricasan is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV)-induced increases in caspase-3 activity and protected human cortical neural progenitors. | |||||||||||||||||||||
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