412319-45-0
Chemical Structure
6-FAM-PEG3-Azide
- CAS No.: 412319-45-0
- Formula:C29H28N4O9
- Molecular Weight:576.55
IUPAC Name: N-(2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)-3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-6-carboxamide
InChIKey: PKYHWLLVYRCZEQ-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2(C3=C(OC4=C2C=CC(O)=C4)C=C(O)C=C3)O5)=C(C=C1)C5=O)NCCOCCOCCOCCN=[N+]=[N-]
Biological Activity: 6-FAM-PEG3-Azide is a PEG-modified azide-functionalized fluorescein derivative that is used for labeling oligonucleotides. 6-FAM-PEG3-Azide is also a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. When 6-FAM-PEG3-Azide is co-incubated with boron clusters in a non-covalent manner, it enhances the cellular uptake and membrane permeability of 6-FAM (HY-66021). 6-FAM-PEG3-azide is applicable for fluorescence bioconjugation and probe development-related research[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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6-FAM-PEG3-Azide | 98.46% | 6-FAM-PEG3-Azide is a PEG-modified azide-functionalized fluorescein derivative that is used for labeling oligonucleotides. 6-FAM-PEG3-Azide is also a click chemistry reagent. It contains an Azide group and can undergo a copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an Alkyne group. When 6-FAM-PEG3-Azide is co-incubated with boron clusters in a non-covalent manner, it enhances the cellular uptake and membrane permeability of 6-FAM (HY-66021). 6-FAM-PEG3-azide is applicable for fluorescence bioconjugation and probe development-related research. | ||||||||||||||||||||
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References
- [1]. Yamamoto S, et al. Hydroxylated iodinated boron clusters: a tunable platform for enhanced membrane transport and biocompatibility. Chemical communications (Cambridge, England). 2026 Jan 13;62(3):879-882.
- [2]. Nakamura H, et al. Enhancing Membrane Permeability of Fluorescein-Type Chromophore Through Covalent Attachment of Chlorinated Dodecaborate. Molecules (Basel, Switzerland). 2024 Nov 17;29(22):5416.
