41498-37-7
41498-37-7
Chemical Structure
GS-389
Synonym(s): (±)-O,O-Dimethylcoclaurine
- CAS No.: 41498-37-7
- Formula:C19H23NO3
- Molecular Weight:313.39
IUPAC Name: 6,7-dimethoxy-1-(4-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline
InChIKey: GXTUEUWFEKEQHJ-UHFFFAOYSA-N
SMILES: COC1=CC=C(CC2NCCC3=C2C=C(OC)C(OC)=C3)C=C1
Biological Activity: GS 389 ((±)-O,O-Dimethylcoclaurine) is a tetrahydroisoquinoline. GS-389 inhibites Cyclic AMP and cyclic AMP dependent phosphodiesterases from rat atrial and ventricular tissue. GS-389 relaxes the contraction induced by phenylephrine and high K+ in rat aortic rings[1].
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GS-389 | GS 389 ((±)-O,O-Dimethylcoclaurine) is a tetrahydroisoquinoline. GS-389 inhibites Cyclic AMP and cyclic AMP dependent phosphodiesterases from rat atrial and ventricular tissue. GS-389 relaxes the contraction induced by phenylephrine and high K+ in rat aortic rings. | |||||||||||||||||||||
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